Portal Vein Thrombosis in Cirrhosis

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Portal vein thrombosis in patients with cirrhosis

Portal vein thrombosis (PVT) is frequent in patients with liver cirrhosis and possible severe complications such as mesenteric ischemia are rare, but can be life-threatening. However, different aspects of clinical relevance, diagnosis and management of PVT are still areas of uncertainty and investigation in international guidelines. In this article, we elaborate on PVT classification, geographi...

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Portal vein thrombosis and survival in patients with cirrhosis.

The effects of occlusive portal vein thrombosis (PVT) on the survival of patients with cirrhosis are unknown. This was a retrospective cohort study at a single center. The main exposure variable was the presence of occlusive PVT. The primary outcome measure was time-dependent mortality. A total of 3295 patients were analyzed, and 148 (4.5%) had PVT. Variables independently predictive of mortali...

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Coagulation Disorders and Portal Vein Thrombosis in Cirrhosis

• Despite prolongation of the prothrombin time, patients with cirrhosis often have decreased protein C and other changes leading to a rebalanced or even hypercoagulable state. • Conventional tests, like INR, are not adequate measures of hemostasis in cirrhotic patients and other tests like Endogenous Thrombin Production (ETP) and Thromboelastography (TEG) need greater standardization and furthe...

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Portal vein thrombosis in liver cirrhosis: incidence, management, and outcome

BACKGROUND Portal vein thrombosis (PVT) is a serious complication in liver cirrhosis with portal hypertension. We examined the treatment, recurrence and prognosis of PVT in cirrhotic patients. METHODS The study subjects were all 90 cirrhotic patients with PVT treated with danaparoid sodium (DS) at our department between July 2007 and September 2016. The mean age was 68 years and mean Child-Pu...

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ژورنال

عنوان ژورنال: Journal of Clinical and Experimental Hepatology

سال: 2014

ISSN: 0973-6883

DOI: 10.1016/j.jceh.2013.12.003